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In this study, 677 levodopa-naive patients in early stages PD were randomized to receive placebo or tolcapone 100 mg three times daily, added to standard doses of levodopa plus carbidopa or benserazide.

Using REXULTI in the last trimester of pregnancy may cause muscle movement problems, medicine withdrawal symptoms, or both of these in your newborn.

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Parkinson's disease causes progressive loss of dopamine production in the brain.

Hallucinations, pathologic gambling and other compulsive behaviors, and orthostatic hypotension are uncommon in patients taking higher doses of pramipexole for Parkinson's disease and are seen even less in patients taking lower doses for RLS.

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Parkinsonian drugs were included (i.

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These drugs significantly reduce the number of limb movements per hour, and improve the subjective quality of sleep.

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The anticholinergic properties of the TCAs may be helpful in PD patients with drooling, overactive bladder and insomnia.

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They are used for treating the unpleasant leg sensations experienced by RLS patients.

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There are three other less commonly used medications that can affect dopamine levels called bromocriptine, pergolide, and cabergoline.

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