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Effects of anemia and left ventricular hypertrophy on cardiovascular disease in patients with chronic kidney disease.

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Partial correction of anemia by ESA treatment of patients with CRF reduces the need for red blood cell (RBC) transfusions and enhances physical functioning.

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Nature and indication: Erythropoiesis-stimulating agent for anemia due to chronic kidney disease in patients on dialysis and not on dialysis; due to Zidovudine in HIV-infected patients; and due to effects of concomitant myelosuppressive chemotherapy, where upon initiation, there is a minimum of two additional months of planned chemotherapy.

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Aapro M, Barnadas A, Leonard RC, Marangolo M, Untch M, Ukarma L, Burger HU, Scherhag A, Osterwalder B (2009a) What is the impact of antithrombotic therapy and risk factors on the frequency of thrombovascular events in patients with metastatic breast cancer receiving epoetin beta?

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