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Is myocardial infarction irreversible? Acute myocardial infarction (MI) indicates irreversible myocardial injury resulting in necrosis of a significant portion of myocardium (generally >1 cm). The term "acute" denotes infarction less than 3-5 days old, when the inflammatory infiltrate is primarily neutrophilic.
What part of the heart is damaged during a heart attack? Myocardial infarction (MI): The damaging or death of an area of the heart muscle (myocardium) resulting from a blocked blood supply to that area. It's also the medical term for a heart attack. Coronary thrombosis: Formation of a clot in one of the arteries that supply blood to the heart muscle.

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